原著論文

  1. Matsuzaka S, Ohba A, Masukawa K, Aoyama M, Morita T, Kizawa Y, Tsuneto S, Shima Y, Miyashita M. Factors associated with the preparedness for bereavement in families of patients with cancer: A secondary analysis of a nationwide bereaved family survey. Psychooncology. 2024 Jan;33(1):e6276. doi: 10.1002/pon.6276.
  2. Tanaka Y, Masukawa K, Sakuramoto H, Kato A, Ishigami Y, Tatsuno J, Ito K, Kizawa Y, Miyashita M. Development of quality indicators for palliative care in intensive care units and pilot testing them via electronic medical record review. J Intensive Care. 2024 Jan 9;12(1):1. doi: 10.1186/s40560-023-00713-z.
  3. Kawasaki Y, Hirai K, Nii M, Kizawa Y, Uchinuno A. Factors Involved in Shared Decision-making Regarding Treatment Selection by Patients With Cancer. Cancer Diagn Progn. 2024 Jan 3;4(1):57-65. doi: 10.21873/cdp.10286.
  4. Sato K, Baba M, Morita T, Masukawa K, Shima Y, Tsuneto S, Kizawa Y, Miyashita M. Continuous Electrocardiographic Monitoring for 24 Hours Before Death in Patients with Terminal Cancer. Am J Hosp Palliat Care. 2023 Dec 13:10499091231222184. doi: 10.1177/10499091231222184. Epub ahead of print.
  5. Kawasaki Y, Hirai K, Nii M, Kizawa Y, Uchinuno A. Actual situation of decision-making support from medical staff when cancer patients make treatment choices. Future Oncol. 2023 Oct;19(33):2263-2272. doi: 10.2217/fon-2023-0335. Epub 2023 Oct 31.
  6. Homma A, Ando M, Hanai N, Harada H, Honma Y, Kanda T, Kano S, Kawakita D, Kiyota N, Kizawa Y, Nakagawa M, Ogawa T, Shinomiya H, Shinozaki T, Suzuki M, Tsuji T, Yasuda K, Zenda S, Kodaira T, Kirita T, Nibu KI. Summary of Japanese clinical practice guidelines for head and neck cancer - 2022 update edited by the Japan society for head and neck cancer. Auris Nasus Larynx. 2023 Jul 21;51(1):174-188. doi: 10.1016/j.anl.2023.07.003. Epub ahead of print.
  7. Hirayama H, Satomi E, Kizawa Y, Miyazaki M, Tagami K, Sekine R, Suzuki K, Yotani N, Sugano K, Abo H, Sakashita A, Sato K, Nakagawa S, Nakazawa Y, Hamano J, Miyashita M. The effect of palliative care team intervention and symptom improvement using patient-reported outcomes: a multicenter prospective observational study. Support Care Cancer. 2023 Jul 3;31(7):439. doi: 10.1007/s00520-023-07912-2.
  8. Mori M, Lin CP, Cheng SY, Suh SY, Takenouchi S, Ng R, Chan H, Kim SH, Chen PJ, Yuen KK, Fujimori M, Yamaguchi T, Hamano J, Kizawa Y, Morita T, Martina D. Communication in Cancer Care in Asia: A Narrative Review. JCO Glob Oncol. 2023 Jun;9:e2200266. doi: 10.1200/GO.22.00266.
  9. Shiraishi R, Kizawa Y, Mori M, Maeda I, Hatano Y, Ishiki H, Miura T, Yokomichi N, Kodama M, Inoue K, Otomo S, Yamaguchi T, Hamano J. Comparison of Symptom Severity and Progression in Advanced Cancer Patients Among Different Care Settings: A Secondary Analysis. Palliat Med Rep. 2023 Jun 23;4(1):139-149. doi: 10.1089/pmr.2023.0011.
  10. Takao A, Arao H, Yamamoto S, Aoki M, Kouda K, Morita T, Kizawa Y, Tsuneto S, Shima Y, Masukawa K, Miyashita M. Nationwide Survey on Caregiver Burden When Supporting Terminal Cancer Patients with Dementia: Bereaved Family Members' Perspective. J Palliat Care. 2023 Jul;38(3):326-335. doi: 10.1177/08258597231169625. Epub 2023 Apr 17.
  11. Lin CP, Peng JK, Hsieh WT, Martina D, Mori M, Takenouchi S, Chan HY, Suh SY, Kim SH, Yuen KK, Kizawa Y, Cheng SY. <i>Letter to the Editor:</i> Improving Access to Advance Care Planning in Current and Future Public Health Emergencies: International Challenges and Recommendations. J Palliat Med. 2023 Apr;26(4):462-463. doi: 10.1089/jpm.2023.0030.
  12. Shimizu Y, Masukawa K, Aoyama M, Morita T, Kizawa Y, Tsuneto S, Shima Y, Miyashita M. The Impact of Stressful Life Events after Bereavement: A Nationwide Cross-sectional Survey. J Pain Symptom Manage. 2023 Apr;65(4):273-284. doi: 10.1016/j.jpainsymman.2022.12.012. Epub 2022 Dec 28.
  13. Naya N, Oka H, Hashimoto S, Morioka Y, Kizawa Y. Real-World Evidence for the Safety and Effectiveness of Naldemedine in the Management of Opioid-Induced Constipation in Patients With Cancer Pain: Post-hoc Subgroup Analysis of Post- marketing Surveillance in Japan. Cureus. 2023 Sep 27;15(9):e46090. doi: 10.7759/cureus.46090.
  14. Hamano J, Shinjo T, Fukumoto K, et al. Unresolved Palliative Care Needs of Elderly Non-Cancer Patients at Home: A Multicenter Prospective Study. J Prim Care Community Heal 2023; 14: 21501319231221430.
  15. Hamano J, Masukawa K, Tsuneto S, et al. Need for Improvement in Death Pronouncements in Palliative Care Units. Palliat Med reports 2023; 4: 350–7.
  16. Takeda Y, Ishiki H, Oyamada S, et al. Symptoms and Prognoses of Patients With Breast Cancer and Malignant Wounds in Palliative Care Units: The Multicenter, Prospective, Observational EASED Study. Am J Hosp Palliat Care 2023; published online Dec 6. DOI:10.1177/10499091231219855.
  17. Amano K, Baracos V, Okamura S, et al. Low serum creatinine as a prognostic marker in advanced cancer. BMJ Support Palliat Care 2023; : spcare-2023-004646.
  18. Kadono T, Ishiki H, Yokomichi N, et al. Malignancy-related ascites in palliative care units: Prognostic factor analysis. BMJ Support Palliat Care 2023; 0: spcare-2023-004286.
  19. Higashibata T, Hamano J, Nagaoka H, et al. Work environmental factors associated with compassion satisfaction and end-of-life care quality among nurses in general wards, palliative care units, and home care settings: A cross-sectional survey. Int J Nurs Stud 2023; 143. DOI:10.1016/j.ijnurstu.2023.104521.
  20. Hamano J, Shima Y, Kizawa Y. Current situation and support need for non-cancer patients’ admission to inpatient hospices/palliative care units in Japan: a nationwide multicenter survey. Ann Palliat Med 2023; 12: 81–9.
  21. Hiratsuka Y, Hamano J, Mori M, Maeda I, Morita T, Suh S-Y. Prediction of Survival in Patients with Advanced Cancer: A Narrative Review and Future Research Priorities. Korean J Hosp Palliat Care 2023; 26: 1–6.
  22. Hiratsuka Y, Oishi T, Miyashita M, et al. Prognostic awareness in Japanese patients with advanced cancer: a follow-up cohort study. Jpn J Clin Oncol 2023; 53: 410–8.
  23. Hamano J, Takeuchi A, Mori M, et al. Comparison of survival times of advanced cancer patients with palliative care at home and in hospital. PLoS One 2023; 18: e0284147.
  24. Hiratsuka Y, Tagami K, Inoue A, Sato M, Matsuda Y, Kosugi K, Kubo E, Natsume M, Ishiki H, Arakawa S, Shimizu M, Yokomichi N, Chiu SW, Shimoda M, Hirayama H, Nishijima K, Ouchi K, Shimoi T, Shigeno T, Yamaguchi T, Miyashita M, Morita T, Satomi E. Prevalence of opioid-induced adverse events across opioids commonly used for analgesic treatment in Japan: a multicenter prospective longitudinal study Support Care Cancer. 2023 Oct 16;31(12):632.
  25. Higashibata T, Kessoku T, Morioka Y, Koretaka Y, Mishima H, Shibahara H, Masuda Y, Ichikawa Y, Nakajima A, Hisanaga T. A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer. Pain Ther. 2023;1-11.
  26. Tagami K, Chiu SW, Kosugi K, Ishiki H, Hiratsuka Y, Shimizu M, Mori M, Kubo E, Ikari T, Arakawa S, Eto T, Shimoda M, Hirayama H, Nishijima K, Ouchi K, Shimoi T, Shigeno T, Yamaguchi T, Miyashita M, Morita T, Inoue A, Satomi E. Cancer Pain Management in Patients Receiving Inpatient Specialized Palliative Care Services.  J Pain Symptom Manage. 2023 (in press).
  27. Hamano J, Hiratsuka Y, Morita T, Kizawa Y, Maeda I, Mori M. Preference of Japanese cancer patients for being informed about their prognosis. Ann Palliat Med 2022; 0: 0–0.
  28. 田口 菜月, 升川 研人, 青山 真帆, 森田 達也, 木澤 義之, 恒藤 暁, 志真 泰夫, 宮下 光令. 緩和ケア病棟における質改善活動の実態と遺族調査におけるアウトカムとの関連.Palliative Care Research18巻3号 Page193-200, 2023. DOI:10.2512/jspm.18.193
  29. 田中 雄太, 加藤 茜, 伊藤 香, 五十嵐 佑子, 木下 里美, 木澤 義之, 宮下 光令. 救急・集中治療領域における医師の緩和ケアに対する認識と実践の障壁 ICUおよび救命救急センターの医師を対象とした自記式質問紙調査の自由記述データを用いた質的内容分. Palliative Care Research8巻2号 Page129-136, 2023. DOI:10.2512/jspm.18.129
  30. 平山 英幸, 里見 絵理子, 木澤 義之, 宮崎 万友子, 田上 恵太, 関根 龍一, 鈴木 梢, 余谷 暢之, 菅野 康二, 安保 博文, 坂下 明大, 佐藤 一樹, 中川 左理, 中澤 葉宇子, 浜野 淳, 宮下 光令. 患者報告型アウトカムを用いた専門的緩和ケアの質評価のための患者登録システムの開発 多施設パイロット調査. Palliative Care Research17巻4号 Page171-180, 2023. DOI:10.2512/jspm.17.171
  31. Hamano J. Prognostic awareness in Japanese patients with advanced cancer: a follow-up cohort study. Japanese journal of clinical oncology. 2023.
  32. Shimizu Y, Masukawa K, Aoyama M, Morita T, Kizawa Y, Tsuneto S, Shima Y, Miyashita M. The Impact of Stressful Life Events after Bereavement: A Nationwide Cross-sectional Survey. J Pain Symptom Manage. 2022 Dec28:S0885-3924(22)01044-2. doi: 10.1016/j.jpainsymman.2022.12.012.
  33. Miyashita J, Shimizu S, Shiraishi R, Mori M, Okawa K, Aita K, Mitsuoka S, Nishikawa M, Kizawa Y, Morita T, Fukuhara S, Ishibashi Y, Shimada C, Norisue Y, Ogino M, Higuchi N, Yamagishi A, Miura Y, Yamamoto Y.  Culturally Adapted Consensus Definition and Action Guideline: Japan's Advance Care Planning. J Pain Symptom Manage. 2022 Dec;64(6):602-613. doi: 10.1016/j.jpainsymman.2022.09.005.
  34. Hamano J, Hiratsuka Y, Morita T, Kizawa Y, Maeda I, Mori M.  Preference of Japanese cancer patients for being informed about their prognosis. Ann Palliat Med. 2022 Nov;11(11):3426-3435. doi: 10.21037/apm-22-772.
  35. Aoyama M, Miyashita M, Masukawa K, Morita T, Kizawa Y, Tsuneto S, Shima Y, Akechi T. Factors related to suicidal ideation among bereaved family members of patients with cancer: Results from a nationwide bereavement survey in Japan. J Affect Disord. 2022 Nov 1;316:91-98. doi: 10.1016/j.jad.2022.08.019.
  36. Ito M, Ishimaru N, Shimokawa T, Kizawa Y.  Risk factors for mortality in aspiration pneumonia: a single-center retrospective observational study.  Monaldi Arch Chest Dis. 2022 Oct 13. doi: 10.4081/monaldi.2022.2305.
  37. Suzuki K, Morita T, Mori M, Azuma Y, Funaki H, Amano K, Imai K, Tanaka K,Kizawa Y, Tsuneto S, Shima Y, Masukawa K, Miyashita M.  Comparative study of clinicians' and family members' perceptions of patients' end-of-life experiences. BMJ Support Palliat Care. 2022 Oct 11:spcare-2022-003883. doi:10.1136/spcare-2022-003883.
  38. Hamano J. Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol. Contemporary clinical trials communications, 2022.
  39. Hatano Y, Morita T, Mori M, Aoyama M, Yoshida S, Amano K, Terabayashi T, Oya K, Tsukuura H, Hiratsuka Y, Maeda I, Kizawa Y, Tsuneto S, Shima Y, Masukawa K, Miyashita M. Association between experiences of advanced cancer patients at the end of life and depression in their bereaved caregivers.  Psychooncology.  2022 Jul;31(7):1243-1252. doi: 10.1002/pon.5915.
  40. Yamaguchi T, Mori M, Maeda I, Matsunuma R, Tanaka-Yagi Y, Nishi T, Kizawa Y,Tsuneto S, Shima Y, Masukawa K, Miyashita M. Comparison of the quality of death between primary malignant brain tumor patients and other cancer patients: results from a nationwide bereavement survey in Japan. J Neurooncol. Jpn J Clin Oncol. 2022 Jul 8;52(7):774-778. doi: 10.1093/jjco/hyac055.
  41. Yamaguchi T, Mori M, Maeda I, Matsunuma R, Tanaka-Yagi Y, Nishi T, Kizawa Y, Tsuneto S, Shima Y, Masukawa K, Miyashita M.The impact of death rattle on bereaved families: not the sound itself, but the resonance with their feelings. Jpn J Clin Oncol. 2022 Jul 8;52(7):774-778. doi: 10.1093/jjco/hyac055.
  42. Aso S, Hayashi N, Sekimoto G, Nakayama N, Tamura K, Yamamoto C, Aoyama M, Morita T, Kizawa Y, Tsuneto S, Shima Y, Miyashita M. Association between temporary discharge from the inpatient palliative care unit and achievement of good death in end-of-life cancer patients: A nationwide survey of bereaved family members. Jpn J Nurs Sci. 2022 Jul;19(3):e12474. doi: 10.1111/jjns.12474.
  43. Ishida K, Sato K, Komatsu H, Morita T, Akechi T, Uchida M, Masukawa K, Igarashi N, Kizawa Y, Tsuneto S, Shima Y, Miyashita M, Ando S.  Nationwide survey on family caregiver-perceived experiences of patients with cancer of unknown primary site. Support Care Cancer. 2022 Jul;30(7):6353-6363. doi:10.1007/s00520-022-07070-x.
  44. Hamano J, Tachikawa H, Takahashi S, et al. Exploration of the impact of the COVID-19 pandemic on the mental health of home health care workers in Japan: a multicenter cross-sectional web-based survey. BMC Prim care 2022; 23: 129.
  45. Oishi A, Hamano J, Boyd K, Murray S. Translation and Cross-Cultural Adaptation of the Supportive and Palliative Care Indicators Tool into Japanese: A Preliminary Report. Palliat. Med. Reports. 2022; 3: 1–5.
  46. Hamano J, Tachikawa H, Takahashi S, et al. Changes in home visit utilization during the COVID-19 pandemic: a multicenter cross-sectional web-based survey. BMC Res Notes 2022; 15: 238.
  47. Hiratsuka Y, Suh SY, Hui D, et al. Are Prognostic Scores Better Than Clinician Judgment? A Prospective Study Using Three Models. J Pain Symptom Manage 2022; published online June. DOI:10.1016/j.jpainsymman.2022.06.008.
  48. Higashibata T, Iwata N, Kazama I, et al. Association of a home-based nursing service during chemotherapy with the transfer to home care immediately after the last chemotherapy treatment in patients with advanced cancer. Jpn J Clin Oncol 2022; 52: 1039–44.
  49. Morioka N, Kashiwagi M, Hamano J. Adherence to Personal Protective Equipment Use in Home-Care Service Agencies During COVID-19 in Japan: A Cross-Sectional Survey. J Am Med Dir Assoc 2022; 23: 930-935.e2.
  50. Odagiri T, Maeda I, Masanori Mori, et al. Effects of Antibiotics on Respiratory Symptoms in Terminally Ill Cancer Patients With Pneumonia: A Multicenter Cohort Study. Am J Hosp Palliat Med 2022; 39: 1082–9.
  51. Kawakami Y, Hamano J. Mortality risks of body mass index and energy intake trajectories in institutionalized elderly people: a retrospective cohort study. BMC Geriatr 2022; 22: 85.
  52. Kim SH, Suh SY, Yoon SJ, et al. The surprise questions using variable time frames in hospitalized patients with advanced cancer. Palliat Support Care 2022; 20: 221–5.
  53. Masumoto S, Sato M, Yamakawa T, et al. Evaluation of changes in prescription among Japanese elderly patients before and after transition to home care. J Gen Fam Med 2022; 23: 94–100.
  54. Higashibata T, Hamano J, Hisanaga T, et al. Does Urinary Catheterization Affect the Quality of Death in Patients with Advanced Cancer? A Secondary Analysis of a Multicenter Prospective Cohort Study. J Palliat Med 2022; 25: 205–12.
  55. Hamano J, Masukawa K, Tsuneto S, et al. Are family relationships associated with family conflict in advanced cancer patients? Psychooncology 2022; 31: 260–70.
  56. Higashibata T, Hamano J, Kessoku T, et al. Rationale and design of a multicenter, double-blinded, randomized, placebo-controlled trial to investigate the effects of naldemedine on opioid-induced constipation for patients with cancer pain: A study protocol. Contemp Clin Trials Commun 2022; 29: 100967.
  57. Imai K, Morita T, Mori M, Yokomichi N, Yamauchi T, Miwa S, Inoue S, Naito AS, Masukawa K, Kizawa Y, Tsuneto S, Shima Y, Otani H, Miyashita M. Family experience of palliative sedation therapy: proportional vs. continuous deep sedation. Support Care Cancer. 2022 May;30(5):3903-3915. doi:10.1007/s00520-021-06745-1.
  58. Hamano J. Exploration of the impact of the COVID-19 pandemic on the mental health of home health care workers in Japan: a multicenter cross-sectional web-based survey. BMC Primary Care, 2022.
  59. Matsunuma R, Matsumoto K, Yamaguchi T, Sakashita A, Kizawa Y. Comprehensive Palliative Care Needs in Outpatients with Chronic Heart Failure: A Japanese Cross-Sectional Study. Palliat Med Rep. 2022 Apr 18;3(1):65-74. doi:10.1089/pmr.2021.0063.
  60. Hayashi E, Aoyama M, Masukawa K, Miyashita M, Morita T, Kizawa Y, Tsuneto S, Shima Y. Bathing in Terminal Care of Cancer Patients and Its Relation to Perceptions of a "Good Death": A Nationwide Bereavement Survey in Japan.  Palliat Med Rep. 2022 Apr 12;3(1):55-64.  doi: 10.1089/pmr.2021.0075.
  61. Hamano J. Translation and Cross-Cultural Adaptation of the Supportive and Palliative Care Indicators Tool into Japanese: A Preliminary Report Palliat Med Rep. 2022
  62. Igarashi Y, Tanaka Y, Ito K, Miyashita M, Kinoshita S, Kato A, Kizawa Y. Current status of palliative care delivery and self-reported practice in ICUs in Japan: a nationwide cross-sectional survey of physician directors. J Intensive Care. 2022 Mar 18;10(1):18.  doi: 10.1186/s40560-022-00605-8.
  63. Hamano J. Effects of Antibiotics on Respiratory Symptoms in Terminally Ill Cancer Patients With Pneumonia: A Multicenter Cohort Study. Am J Hospice Palliat Care, 2022.
  64. Hamano J. Adherence to Personal Protective Equipment Use in Home-Care Service Agencies During COVID-19 in Japan: A Cross-Sectional Survey, JAMDA, 2022.
  65. Hamano J. Mortality risks of body mass index and energy intake trajectories in institutionalized elderly people: a retrospective cohort study. BMC geriatrics, 2022.
  66. Chitose H, Kuwana M, Miura T, Inoue M, Nagasu Y, Shimizu R, Hattori Y, Uehara Y, Kosugi K, Matsumoto Y. A Japanese Nationwide Survey of Nutritional Counseling for Cancer Patients and Risk Factors of Burnout among Registered Dietitians. Palliat Med Rep. 2022;3(1):211-219.
  67. Uneno Y, Kotera Y, Fujisawa D, Kataoka Y, Kosugi K, Murata N, Kessoku T, Ozaki A, Miyatake H, Muto M. Development of a novel COMPAssion focused online psyChoTherapy for bereaved informal caregivers: the COMPACT feasibility trial protocol. BMJ Open. 2022;12(12):e067187.
  68. Usui Y, Kosugi K, Nishiguchi Y, Usui Y, Miura T, Fujisawa D, Uehara Y, Kawaguchi T, Izumi K, Takehana J, Matsumoto Y. Parenting experiences of cancer patients with minor children and their conversations about the possibility of death: a cross-sectional web-based survey for an online cancer community. Support Care Cancer. 2022;30(9):7715-7720.
  69. Odagiri T, Maeda I, Masanori Mori, Morita T, Kaneishi K,Nozato J,Kosugi K, Higashibata T, Hamano J, Shimoinaba J, Nishi T, Kawashima N. Effects of Antibiotics on Respiratory Symptoms in Terminally Ill Cancer Patients With Pneumonia: A Multicenter Cohort Study. Am J Hosp Palliat Care. 2022 Sep;39(9):1082-1089.
  70. Usui Y, Miura T, Kawaguchi T, Kosugi K, Uehara Y, Kato M, Kosugi T, Sone M, Nakamura N, Mizushima A, Miyashita M, Morita T, Yamaguchi T, Matsumoto Y, Satomi E. Palliative care physicians' recognition of patients after immune checkpoint inhibitors and immune-related adverse events. Support Care Cancer. 2022; 30:775-784.
  71. 野本 瑠奈; 福島 紘子; 城戸 崇裕; 大戸 達之; 田中 磨衣; 岩淵 敦; 榎園 崇; 田中 竜也; 増田 洋亮; 岩田 直子; 吉本 尚; 濵野 淳; 高田 英俊. 小児神経疾患患者における当院の移行実績. 茨城県立病院医学雑誌 2022; 39: 1–7.
  72. Hosoi T, Ozone S, Hamano J, Maruo K, Maeno T. Prediction Models for Impending Death Using Physical Signs and Vital Signs in Noncancer Patients: A Prospective Longitudinal Observational Study. Palliat Med Reports 2021; 2: 287–95.
  73. Naito AS, Morita T, Imai K, et al. Development of a scoring system to determine proportional appropriateness of continuous deep sedation: A concept-of-proof study. J Palliat Med 2021; 24: 1539–44.
  74. Higashibata T, Hisanaga T, Hagiwara S, et al. Differences among institutions in the prevalence of and indications for urinary catheterization of advanced cancer patients at palliative care units: A multicenter prospective cohort study (EASED). Palliat Med 2021; 35: 799–805.
  75. Masumoto S, Sato M, Momo K, et al. Development of medication regimen complexity index: Japanese version and application in elderly patients. Int J Clin Pharm 2021; 43: 858–63.
  76. Hamano J, Morita T, Igarashi N, Shima Y, Miyashita M. The association of family functioning and psychological distress in the bereaved families of patients with advanced cancer: a nationwide survey of bereaved family members. Psychooncology 2021; 30: 74–83.
  77. Ishiki H, Hamano J, Nagaoka H, et al. Prevalence of Extrapyramidal Symptoms in Cancer Patients Referred to Palliative Care: A Multicenter Observational Study (JORTC PAL12). Am J Hosp Palliat Med 2021; 38: 823–9.
  78. Hamano J, Mori M, Ozawa T, et al. Comparison of the prevalence and associated factors of hyperactive delirium in advanced cancer patients between inpatient palliative care and palliative home care. Cancer Med 2021; 10: 1166–79.
  79. Nagaoka H, Momo K, Hamano J, Kizawa Y, et al. Effects of an Indomethacin Oral Spray on Pain Due to Oral Mucositis in Cancer Patients Treated With Radiotherapy and Chemotherapy: A Double-Blind, Randomized, Placebo-Controlled Trial (JORTC-PAL04). J Pain Symptom Manage 2021; 62: 537–44.
  80. Hiratsuka R, Aoyama M, Masukawa K, et al. The Association of Family Functioning With Possible Major Depressive Disorders and Complicated Grief Among Bereaved Family Members of Patients With Cancer: Results From the J-HOPE4 Study, a Nationwide Cross-Sectional Follow-Up Survey in Japan. J Pain Symptom Manage 2021; 62: 1154–64.
  81. Arakawa S, Amano K, Oyamada S, Maeda I, Ishiki H, Miura T, Hatano Y, Naito AS, Sato M, Ito T, Kosugi K, Miyake S, Morita T, Mori M; East-Asian Collaborative Cross-Cultural Study To Elucidate the Dying Process (EASED) Investigators. Effects of parenteral nutrition and hydration on survival in advanced cancer patients with malignant bowel obstruction: secondary analysis of a multicenter prospective cohort study. Support Care Cancer. 2021; 29: 7541-7549.
  82. Kosugi K, Nishiguchi Y, Miura T, Fujisawa D, Kawaguchi T, Izumi K, Takehana J, Uehara Y, Usui Y, Terada T, Inoue Y, Natsume M, Yajima MY, Watanabe YS, Okizaki A, Matsushima E, Matsumoto Y. Association Between Loneliness and the Frequency of Using Online Peer Support Groups Among Cancer Patients With Minor Children: A Cross-Sectional Web-Based Study. J Pain Symptom Manage 2021; 61:955-962.
  83. Imai K, Morita T, Akechi T, et al. The Principles of Revised Clinical Guidelines about Palliative Sedation Therapy of the Japanese Society for Palliative Medicine. J Palliat Med 2020; 23. DOI:10.1089/jpm.2019.0626.
  84. Haruta J, Ozone S, Hamano J. Doctors’ professional identity and socialisation from medical students to staff doctors in Japan: Narrative analysis in qualitative research from a family physician perspective. BMJ Open. 2020; 10. DOI:10.1136/bmjopen-2019-035300.
  85. Morioka S, Mori M, Suzuki T, Yokomichi M, Hamano J, Morita T. Diversity of physicians’ attitudes toward the management of infectious diseases in terminally ill patients with cancer. J. Hosp. Infect. 2020; 105: 582–4.
  86. Morioka S, Mori M, Suzuki T, Yokomichi M, Hamano J, Morita T. Determinants of Physicians’ Attitudes Toward the Management of Infectious Diseases in Terminally Ill Patients With Cancer. J Pain Symptom Manage 2020; 60: 1109-1116.e2.
  87. Liao JY, Chen PJ, Wu YL, et al. HOme-based Longitudinal Investigation of the multidiSciplinary Team Integrated Care (HOLISTIC): protocol of a prospective nationwide cohort study. BMC Geriatr 2020; 20. DOI:10.1186/s12877-020-01920-1.
  88. Hosoi T, Ozone S, Hamano J. Variations in vital signs at the end of life in non-cancer patients: A retrospective study. Ann Palliat Med 2020; 9: 2678–83.
  89. Hamano J, Hanari K, Tamiya N. Attitudes and Other Factors Influencing End-of-Life Discussion by Physicians, Nurses, and Care Staff: A Nationwide Survey in Japan. Am J Hosp Palliat Care 2020; 37: 258–65.
  90. Hamano J, Hanari K, Tamiya N. End-of-life care preferences of the general public and recommendations of healthcare providers: A nationwide survey in Japan. BMC Palliat Care 2020; 19: 38.
  91. Hosoi T, Ozone S, Hamano J. Survival time after marked reduction in oral intake in terminally ill noncancer patients: A retrospective study. J Gen Fam Med 2020; 21: 9–14.
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